Yini ukusetshenziswa kwethebhulethi ye-calcium acetate?

Amaphilisi we-calcium acetate Ingabe umuthi ovame ukubekiwe osebenza ngezinhloso ezithile zokwelashwa, ikakhulukazi ekuphatheni izimo ezithile zezempilo. Njengosawoti we-calcium we-acetic acid, i-calcium acetate inezakhiwo ezenza zisebenze kakhulu ekubhekaneni nokungalingani kwamaminerali emzimbeni. Kulesi sihloko, sizohlola ukusetshenziswa, izinzuzo, izindlela zokwenziwa, kanye nokucatshangelwa okubalulekile okuhlobene namathebulethi we-calcium acetate.

Ukusetshenziswa Okuyisisekelo: Ukuphathwa kwe-hyperphosphatemia

Ukusetshenziswa okuyisisekelo kwamathebulethi e-calcium acetate yi- Ukuphathwa kwe-hyperphosphatemia, Isimo esibonakaliswa ngamazinga aphakeme we-phosphate egazini. IHyperphosphatemia ibonakala kakhulu kubantu abanesifo esingamahlalakhona (CKD), ikakhulukazi labo ababhekene ne-dialysis.

Kungani i-hyperphosphatemia ikhathazeka?

Ku-CKD, izinso zilahlekelwa amandla abo okuthola i-phosphate ngokweqile. Lokhu kuholela ekuqongeleleni kwe-phosphate egazini, okungaholela ezinkingeni ezinjengokuthi:

• Ukubalwa kwemithambo yegazi nezicubu: Lokhu kwandisa ingozi yesifo senhliziyo.
• Ukuphazamiseka kwamathambo: I-phosphate eyeqile iphazamisa ibhalansi ebucayi ye-calcium ne-phosphorus, efaka isandla emathanjeni abuthaka kanye nemibandela efana ne-renal osteodystrophy.

Amaphilisi we-calcium acetate asiza ukulawula amazinga e-phosphate egazini, anciphise lezi zingozi kanye nokwenza ngcono imiphumela yeziguli.

Indlela Yokusebenza: Isebenza kanjani amaphilisi e-calcium acetate?

Izenzo ze-calcium acetate njenge I-Phosphate Binder. Lapho kuthathwa ngokudla, i-calcium kwithebhulethi ibopha i-phosphate ekudleni. Lokhu okubophayo kwakha i-infoluble compound, i-phosphate ye-calcium, eyayikhishwe emzimbeni ngesitulo kunokuba angeniswe egazini. Ngokunciphisa ukumuncwa kwe-phosphate, i-calcium acetate yehlisa ngempumelelo amazinga egazi le-phosphate.

Izinzuzo ezingezekile

1. Ukusekelwa kwe-calcium:

Ngenkathi ngokuyinhloko isetshenziswa njenge-phosphate bender, i-calcium acetate ibuye inikeze ukusekelwa kwe-calcium. Lokhu kuzuzisa ikakhulukazi abantu abanokushoda kwe-calcium, ngoba kusiza ukugcina amathambo namazinyo anempilo.

2. Ukuvimbela i-hyperparathroudism yesibili:

Ku-CKD, ukungalingani nge-calcium ne-phosphate kungadala ukungabhebhetheki ngokweqile kwe-parathyroid glands (i-hyperperreaparathroidism). Ngokusebenzisa la mazinga amaminerali, i-calcium acetate ingasiza ukuvikela noma ukuphatha lesi simo.

Umthamo nokuphatha

Amaphilisi we-calcium acetate athathwa ngokuvamile Ngokudla Ukuqinisekisa ukuthi baxhumana ne-phosphate yokudla ekhona ekudleni. Umthamo uhlukaniswe ngakunye ngokususelwa kumazinga wesiguli we-phosphate, imikhuba yokudla, kanye nesimo sempilo sonke. Ukuqapha njalo kwe-phosphate yegazi kanye namazinga we-calcium kubalulekile ukuze uguqule umthamo futhi ugweme izinkinga.

Izindlela zokuqapha kanye nokucatshangelwa

1. Ingozi ye-hypercalcemia:

Umphumela owodwa we-Calcium Acetate yi-hypercalcemia noma amazinga aphakanyisiwe egazini. Izimpawu ze-hypercalcemia zingafaka isicanucanu, ukugabha, ukudideka, ubuthakathaka bemisipha, kanye ne-arrythmias. Ukuhlolwa kwegazi njalo kubalulekile ukuqapha amazinga we-calcium futhi uvikele lesi simo.

2. Ukusebenzisana kwezidakamizwa:

I-calcium acetate ingasebenzisana neminye imithi ngokunciphisa ukumuncwa kwazo. Isibonelo, kungathinta ukusebenza kwama-antibiotic afana ne-tetracyclines nama-fluoroquequicolone, kanye nemithi ye-thyroid. Iziguli kufanele zazise umhlinzeki wazo wezokunakekelwa kwezempilo ngayo yonke imithi abayithathayo.

3. Hhayi ukusetshenziswa e-hypophosphatemia:

I-calcium acetate ayilungele abantu abanamazinga we-phosphate aphansi (i-hypophosphatemia) noma izimo lapho ukwengeza kwe-calcium kungqubuzana khona.

Ngubani okufanele asebenzise amaphilisi we-calcium acetate?

Amaphilisi we-calcium acetate anqunyelwe ikakhulukazi abantu abane:

• Isifo Sezinso Esingamahlalakhona (CKD) ku-dialysis.
• Amazinga we-phosphate aphakeme ngenxa yomsebenzi wezinso.

Lawa mathebhulethi kufanele asetshenziswe ngaphansi kokuqondisa komhlinzeki wezokunakekelwa kwempilo ukuze aqinisekise ukuphepha nokusebenza ngempumelelo.

Ezinye izindlela ze-calcium acetate

Ngenkathi i-calcium acetate iyi-binder ye-phosphate esetshenziswa kabanzi, ezinye izindlela zitholakala kubantu abangakwazi ukukubekezelela noma basengozini ye-hypercalcemia. Lokhu kufaka phakathi:

• Ama-mosphate asekelwe ama-phosphate ama-phosphate njenge-nanthaner noma i-lanthanum carbonate.
• Ukulungiswa kokudla ukunciphisa ukudla kwe-phosphate.

Abahlinzeki bezokunakekelwa kwezempilo banquma inketho yokwelashwa engcono kakhulu ngokususelwa kwizidingo ezithile zesiguli nomlando wezokwelapha.

Ukugcina

Amaphilisi we-calcium acetate ayimithi ebalulekile yokuphatha i-hyperphosphatemia kubantu abanesifo sozinso obungapheli. Ngokusebenza njenge-phropate bheripha, basiza ukulawula amazinga we-phosphate ama-phosphate, bavikele ezinkambeni, futhi bathuthukise impilo yonke. Kodwa-ke, njenganoma yimuphi umuthi, badinga ukusetshenziswa ngokucophelela nokuqapha ukugwema imiphumela emibi futhi baqinisekise inzuzo ephezulu.

Kulawo abekiwe i-calcium acetate, ukuqonda inhloso yawo kanye nokunamathela ekweluleni kwezokwelapha kubalulekile. Ngokuphathwa okufanele, lo muthi udlala indima ebalulekile ekusekeleni impilo yezinso futhi avimbele ukungalingani kwamaminerali.